The effect of presynaptic muscarinic Acetylcholine receptor (mAChR) on neural code and odor discrimination in the Drosophila Melanogaster
Autoreceptors are pre-synaptic receptors, sensitive to the neuron’s own neurotransmitters. They exist in all known neuronal families and usually take a role in negative feedback mechanisms.
It has been shown that muscarinic Acetylcholine autoreceptor M2 (M2R) in mice, are important for maintaining constant kinetics of release, independent of pre-synaptic calcium levels.
I'm studying the role of Dm1, a muscarinic Acetylcholine autoreceptor (mAChR) in the Drosophila Melanogaster's olfactory system: its effect on neural activity and behavior.