Developing gene therapy for severe epilepsy

Position details

Developing gene therapy for severe epilepsy

The Laboratory of Moran Rubinstein  

Is looking for MSc, PhD, PostDoc, Project student, Rotation/Project

Position title

Dravet syndrome is an intractable childhood-onset epilepsy caused by loss of function mutations in Nav1.1. Dravet syndrome symptoms begin during the first year of life, with seizures often associated with fever, and progress to refractory and frequent seizures. Additionally, Dravet patients develop cognitive deficit, autistic-like behaviors, hyperactivity and premature death. In collaboration with two other European labs, we aim to develop gene therapy with the overall goal to cure Dravet

Job description

We are looking for talented, motivated and hard-working students and postdocs. Our studies combine studies in mice, in vivo and brain slice electrophysiology together with behavioural experiments.