Sagol faculty


Prof. Yosef Shiloh

Dept. of Human Molecular Genetics and Biochemistry, Sackler School of Medicine

Tel: 03-6409760



Research topic: The human genetic disorder ataxia-telangiectasia (A-T) and the DNA damage response

Research methods: Cell biology, biochemistry, microscopic imaging, proteomics

Main projects in the lab include:

  1. Identification of novel branches of the ATM-mediated DNA damage response
  2. The organization of the DNA damage response in the nervous system
  3. The origins of the cerebellar degeneration in A-T
  4. Creating animal models representing defective DNA damage response in specific tissues, with emphasis on the nervous system