Tel Aviv University researchers have identified the mechanism that causes the death of neurons in Familial Dysautonomia

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 Tel Aviv University researchers have identified the mechanism that causes the death of neurons in Familial Dysautonomia

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Scientists Harness Virtual Reality to Teach Damaged Limbs

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Scientists at Tel Aviv University, led by Prof. Roy Mukamel, have demonstrated that the brain can be “tricked” into learning a physical skill without any corporeal practice at all, using virtual reality. If developed into a technology in the future, it could be useful for stroke victims, for instance, who need to recover motoric capabilities.
read more: http://www.haaretz.com/science-and-health/1.758774

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Brain Researcher featured in Haaretz – Prof. Talma Hendler and Prof. Inna Slutsky

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A unique type of GSK-3 inhibitor brings new opportunities to the clinic

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This Podcast features an interview with Hagit Eldar-Finkelman, author of a Research Article that appears in the 15 November 2016 issue of Science Signaling, about a newly developed inhibitor of glycogen synthase kinase 3 (GSK-3). GSK-3 participates in several signaling networks and has been implicated in various pathologies, including neurodegenerative diseases, cognitive impairments, and cancer. Licht-Murava et al. developed L807mts, a substrate-competitive peptide inhibitor that blocks GSK-3 activity through an unusual mechanism. L807mts not only bound to the substrate recognition domain of GSK-3, it was also phosphorylated by the kinase. This phosphorylated form of L807mts remained associated with GSK-3 and inhibited GSK-3 activity. L807mts treatment reduced cellular, cognitive, and behavioral symptoms in a mouse model of Alzheimer’s disease. L807mts is an advance in kinase inhibitor development because it is both highly specific and very potent.

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