Ziv Ben Zion

PhD student at Prof. Talma Hendler’s laboratory

Research title
Neurobehavioral Moderators of Post-Traumatic Disease Trajectories


Research project

Post-traumatic stress disorder (PTSD) symptoms are often observed shortly after sustaining a traumatic event. Individuals differ in the trajectory of these symptoms, leading to full, partial, or non-recovery from initial reactions. Impairments in emotional-regulatory functions that influence the processing of stressful events may contribute to the development of long-term PTSD. Neural mechanism through which these impairments mediate the impact of trauma may include hyperactive emotional reactivity coupled with dysfunctional regulatory circuitry. Studies to date have yet to longitudinally explore the neural mechanism of PTSD symptom trajectories over the first year after trauma exposure. In my PhD research, we aim to prospectively probe specific components of the stress response network in trauma-exposed individuals during 14 months following the traumatic event, tracking both symptomatic development, the underlying brain plasticity, and putative brain tissue of function vulnerability factors. Within the study, subjects are assessed shortly after being admitted to Emergency Department following potentially traumatic events and are subsequently evaluated at three time points (one, six, and fourteen months from the trauma), for trauma-related symptoms and contemporaneous brain functions and structures. The combination of behavioral symptoms, specific brain functions and brain structures, and their time-dependent progression, may identify potential targets for preventive neurocognitive intervention for PTSD.


Meetings

  • Poster Presentation - Self-Modulation of Deep Brain Activity: Novel Neurofeedback Treatment for Affective Instability in Premenstrual Dysphoric Disorder (PMDD). “Talk 2 UR Brain”-Advances in Neurofeedback: Research and Practice, Tel Aviv University, Israel, November 22nd, 2015.

  • Poster Presentation - Transcranial Electrical Stimulation Targeting vmPFC Leads to Increased Acceptance Rates in the Anger-Infused Ultimatum Game. Current Advances in Brain Stimulation and Neurofeedback, Tel Aviv University, Israel, November 9th, 2016.

  • Poster Presentation - Transcranial Electrical Stimulation Targeting vmPFC Leads to Increased Acceptance Rates in the Anger-Infused Ultimatum Game (UG). Cognitive Improvement: Approaches, Mechanisms and Applications, Bar-Ilan University, Israel, May 21-24, 2017.

  • Poster Presentation - Electrical Stimulation of the Medial Prefrontal Cortex to Regulate Induced Anger. Organization for Human Brain Mapping (OHBM), Vancouver Convention Centre, British Columbia, Canada, June 25-29, 2017.


Awards

  • Dean’s List, Sagol School of Neuroscience, Tel-Aviv University (2014)

  • Scholarship Award for Excellence in Academic Studies, Rotary International and Municipal Council, Kiryat Tivon (2014)

    Double Major B.Sc. in Biology and in Psychology with an emphasis on Neuroscience, Summa Cum Laude (GPA: 96), Sagol School of Neuroscience, Tel-Aviv University (2015)

    Traveling Grant for Cooperation between Laboratories Abroad, on behalf of Sagol School of Neuroscience & Adams Super Center for Brain Studies (2017)


Contact
zivbenzion@mail.tau.ac.il


Research Categories: Affective neuroscience, Behavioral Neuroscience, Cognitive neuroscience