Facilitation of learning and memory in humans
The human brain is known by its ability to modify and update existing memories. Interestingly, following the initial acquisition of a new skill, we are able to increase or decrease its memory, and even to generalize it by extending the memory trace to novel boundaries beyond its originally encoded features.
In order to explore this flexibility of memories, we utilize the framework of reactivation-reconsolidation, which is known to allow modifications of consolidated memory traces. This framework stems from studies at the synaptic level, showing that even fully consolidated memories, presumably stabilized, can be updated if they are reactivated. The ability to update such memories is limited to a time window, after which the memory returns to a stable state through the process of reconsolidation.
My research is aimed at revealing methods of memory facilitation, together with the neural mechanisms underlying memory modification, through a combination of behavioral studies, neuroimaging studies (focused on fMRI changes in functional connectivity), and neuromodulation studies, using non-invasive brain stimulation (TMS).
Herszage J.*, Dayan E.*, Laor Maayany R., Sharon H., Censor N. (November 2017). Casual prefrontal cortex neuromodulation of reinforced skill learning. Poster presentation delivered at the SfN annual meeting, Washington D.C., USA.
Herszage J., Censor N. (February 2017). Long-term prevention of interference using the memory reactivation-reconsolidation framework. Poster presentation delivered at the 4th Conference on Cognition Research of the Israeli Society for Cognitive Psychology, Akko, Israel.
Herszage J., Censor N. (December 2016). Memory reactivation enables long-term prevention of interference. Poster presentation delivered at the Israeli Society for Neuroscience meeting, Eilat, Israel.
Herszage, J., & Censor, N. (2017). Memory Reactivation Enables Long-Term Prevention of Interference. Current Biology, 27(10), 1529-1534.