Join us at Sheppes Emotion & Self Regulation lab

Published by: Gal Sheppes

E-mail address: sheppes@post.tau.ac.il

Join our lab!
The Emotion & Self Regulation Lab seeks to integrate basic and applied science in order to study the underlying mechanisms of emotion regulation and self-regulation among healthy and clinical populations.

Open positions: Project for Sagol B.Sc students
Rotation for Sagol M.Sc students
Ph.D or Post-doc students

For more details and applying please read the attached pdf and contact our lab manager Leemor at leemorzucker@mail.tau.ac.il

Field of research: behavioral Neuroscience, cognitive neuroscience

Additional information is available in this file

Laboratory website link

Advanced MRI methods for the assessment of the human cerebral vascular system

Published by: Dafna Ben Bashat

E-mail address: dafnab@tlvmc.gov.il

Accurate and comprehensive assessment of the cerebrovascular system is highly important in clinical setup, for the assessment of tissue integrity and disease severity; identification of tissue at risk; and prediction of treatment response. Characterization of the cerebrovascular system includes quantitative measures such as blood flow and perfusion, assessment of the presence, source and potency of collaterals, and imaging and assessment of perfusion in the different vascular territories. Using MRI, several methods have been proposed to indirectly measure various vascular parameters, yet many of these methods still rely on qualitative assessment and require the input of an expert neuro-radiologist when applied in clinical practice.
The project will focus on developing and applying methods for quantitative assessment of the brain's vascular system in healthy controls and in patients with vascular pathologies.
The research is being conducted at the Functional Brain Center at Tel Aviv Sourasky Medical Center the supervision of Dr Dafna Ben Bashat.

Field of research: brain disorders

Additional information is available in this file

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Open research position in the high-level cognition lab

Published by: Liad Mudrik

E-mail address: mudrikli@tau.ac.il

We are seeking highly motivated graduate students to lead our research of high-level cognition. We focus on two main phenomena: semantic integration, and conscious awareness. More specifically, we ask what enables the process of judging the relations between two objects or concepts, what are the functions of consciousness and what are its neural substrates. To tackle these questions, we use behavioral studies and electrophysiology (EEG and intracranial recordings).

Field of research: cognitive neuroscience

Additional information is available in this file

Laboratory website link

The Nathan Dascal’s lab is seeking for enthusiastic, motivated graduate students and postdocs.

Published by: Nathan Dascal

E-mail address: dascaln@tauex.tau.ac.il

The Nathan Dascal’s lab is seeking for enthusiastic, motivated Ph.D. students and postdocs. We investigate how hormones, neurotransmitters and drugs regulate the function of cardiac cells and neurons in health and disease, by acting on ion channels and neurotransmitter receptors.
For additional details, visit: http://medicine.mytau.org/dascal/
● Molecular and neuronal mechanisms of bipolar disorder (BPD) and related drug actions.
● Mechanisms of regulation and function of Ca2+ channels.
● Mechanisms of disease caused by dysfunction of GIRK K+ channels.
All projects involve a multidisciplinary approach that combines electrophysiology, biophysics, advanced biochemistry, fluorescent microscopy, cytochemistry, and mathematical and structural modeling. Studies are done in cultured immortalized cells, cardiomyocytes, brain slices and heterologous models.
Send C.V. to Prof. Nathan Dascal at dascaln@post.tau.ac.il, or call 03-640-5743

Field of research: brain disorders, cellular / molecular neuroscience

Additional information is available in this file

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We are looking for enthusiastic PhD and MSc students!

Published by: Yoni Haitin

E-mail address: yhaitin@post.tau.ac.il

Our lab is interested in the effects ion channels have of the activity of immune, cancer and neuronal cells.

Ion channels are membrane-embedded molecular machines that enable cells to communicate with the extracellular world. In the immune system, microglial cells, the macrophages of the brain, express a variety of ion channels, which ignite and mediate cellular responses. However, microglial activation can be a double-edged sword, exacerbating acute brain pathologies including stroke, and neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases.
Moreover, due to their newly discovered roles in cell-cycle regulation, ion channels gain increasing attention as prominent targets for cancer therapy.

Our research focuses on how anion selective channels, one of the least understood families of ion channels, contribute to brain function and immune response, and regulatory mechanisms of cancer-associated channel mutants. Using a combined multifaceted approach, which includes structural, electrophysiological and fluorescent techniques, we decipher the molecular mechanisms governing the activity and regulation of anion channels, and explore how they contribute to normal and pathophysiological microglial function.

For more information please contact Yoni Haitin: yhaitin@post.tau.ac.il

Field of research: brain disorders, cellular / molecular neuroscience, neurodevelopment and neurogenetics

Additional information is available in this file

Laboratory website link