Research topic: The human genetic disorder ataxia-telangiectasia (A-T) and the DNA damage response
Research methods: Cell biology, biochemistry, microscopic imaging, proteomics
Main projects in the lab include:
- Identification of novel branches of the ATM-mediated DNA damage response
- The organization of the DNA damage response in the nervous system
- The origins of the cerebellar degeneration in A-T
- Creating animal models representing defective DNA damage response in specific tissues, with emphasis on the nervous system