Research topic: The human genetic disorder ataxia-telangiectasia (A-T) and the DNA damage response

Research methods: Cell biology, biochemistry, microscopic imaging, proteomics

Main projects in the lab include:

1. Identification of novel branches of the ATM-mediated DNA damage response
2. The organization of the DNA damage response in the nervous system
3. The origins of the cerebellar degeneration in A-T
4. Creating animal models representing defective DNA damage response in specific tissues, with emphasis on the nervous system