Sagol faculty

rotenstreich-ygal

Prof. Ygal Rotenstreich

Goldschleger Eye Institute


Tel: 03-5308132

Email

Research topic:

  • The eye as a window to the brain – using retinal structure and function measurements as novel early and objective biomarkers for brain neurodegeneration diseases (e.g. Alzheimer’s disease and multiple sclerosis), brain injuries and brain tumors.
  • Development of novel treatments for neuroretinal degeneration
  • Development of innovative diagnostic tools for macular, retinal degeneration and optic nerve diseases

Research methods:

  • Clinical trials – ophthalmic, imaging and pupillometry analyses
  • Animal research including transgenic rodent models for neuroretinal diseases
  • Molecular biology, tissue cultures and advanced in vivo imaging

Projects in the lab include:

  • Retinal structure and function measurements as novel objective biomarkers for Alzheimer’s disease
  • Chromatic multifocal pupillometry for objective assessment of optic neuritis and multiple sclerosis
  • Chromatic multifocal pupillometry for objective assessment and early detection of changes in intracranial pressure and acute brain injury
  • Development of stem cell therapies for neuroretinal degeneration – pre-clinical studies and clinical trials
  • The role of microglia activation in neuroretinal degeneration and development of microglia-blocking treatments for incurable retina degeneration
  • Chromatic multifocal pupillometry – an innovative diagnostic tool for objective assessment of macular, retinal degeneration and optic nerve diseases

Joint projects with other Faculty members in the Sagol School of Neuroscience:

  • Retinal Structure and function as novel objective biomarkers for Alzheimer’s disease – in collaboration with Prof. Michal Beeri and Dr. Ramit Ravona-Springer