Research topic: The molecular mechanisms underlying the association between Gaucher disease and Parkinson’s disease
Research methods: Molecular techniques (cloning, transfections, DNA, RNA and protein methodology), cell biology techniques (microscopy), Drosophila work
Projects in the lab include:
- ER stress and UPR as the links between Gaucher disease and Parkinson’s disease.
- Neuronopathic Gaucher disease in Drosophila melanogater as a model system.
- Treatments for neuronopathic Gaucher disease (drug delivery to the brain).
- Use of Drosophila malanogaster as a platform to screen and validate efficiency of pharmacological chaperones.