Research topic: Elucidating the molecular mechanisms of myelin formation and maintenance in the CNS using a mouse model for Vanishing White Matter (VWM) disease; Differentiation of stem cells to the neuronal lineage; Translational control in learning and memory; Translational Control of Gene Expression in Health and Disease.
Research methods: Molecular and Cellular Biology, Biochemistry, Immuno-histochemistry, Confocal & Electron Microscopy; Behavioral studies, MRI, Stem Cells Biology, DNA microarrays and quantitative Real-Time PCR.
Main projects in the lab include:
- Differentiation of Embryonic Stem Cells to myelinating cells
- Development of a drug for the treatment of Vanishing White Matter disease
- Effect of stress on myelin maintenance
- Translational control in Learning and memory