- Neurobiology of genetic neurodevelopmental disorders such as Williams syndrome and autism spectrum disorders.
- Dissecting neural circuits and brain regions’ roles in anxiety-like and social behavior.
- Therapeutic approaches to improve behavioral abnormalities in mouse models for psychiatric disorders.
- Molecular and cellular biology
- In vivo optogenetics and pharmacogenetics
- Behavioral tests
- Stereotaxic surgical techniques for gene delivery
- Nucleic acid methods
- Transgenic and conditional knockout mouse models
- Histology and microscopy
- In vitro cell-based assays
Projects in the lab include:
- In vivo optogenetic manipulation of social behavior abnormalities in mouse models for psychiatric disorders
- Gene-rescue treatments to restore behavior and physiology in mouse models for psychiatric disorders
- Defining the postnatal developmental and functional roles of genes in mouse models for psychiatric disorders
- Pharmacological and pharmacogenetical studies to treat psychiatric disorders
- Neuron-glia interactions and their role in the pathophysiology of psychiatric disorders
- Production and characterization of novel mouse models for genetic neuropsychiatric disorders