Sagol faculty

Ashery-Padan-Ruthie-sagol-profile

Prof. Ruth Ashery-Padan

Dept. of Human Molecular Genetics and Biochemistry, Sackler School of Medicine


Tel: 03-6409331

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Research topic: We focus on understanding the molecular mechanisms that control the development of the visual system in mammals. Specifically we investigate the mechanisms that regulate cell-fate decisions, normal differentiation and survival of retinal neurons. Our studies are important for understanding the development of the eye and disease conditions that lead to vision loss.

Research methods: Transgenic mice; confocal microscopy; deep sequencing; retinal cultures; functional studies of genes in vivo and in cultures; analysis of promoter structure and activity, DNA microarrays.

Main projects in the lab include:

  1. Study of gene networks controlling cell-fate decisions in retinal neurogenesis
  2. Study function of transcription factors and micro-RNA in specific retinal neurons
  3. Investigating the development of ocular structures that are essential for normal vision; lens, cornea and the pigmented cell types of the eye