Sagol faculty

Ruban-Angela

Dr. Angela Ruban

Nursing Dept., Steyer School of Health Professions, Sackler Faculty of Medicine


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Research topic: Role of Glutamate excitotoxicity in neurodegenerative and malignant diseases

Research methods:  In-vivo MRI/MRS, intracranial mouse and rat tumor models, brain metastatic animal models, Immunohistochemistry, drug sustained release (Osmotic pumps). Retrospective/prospective clinical trials.

Main projects in the lab include:

  1. Blood glutamate scavenging as a novel neuroprotective treatment.
  2. Elucidating the role of blood liver enzyme and glutamate levels and the pathophysiology of neurodegenerative and malignant diseases.
  3. Blood glutamate scavenging in the prevention of melanoma invasiveness.